Fluid management in diabetic patients

Objective: To determine hypothesize Ringer's lactate is superior to 0.9% sodium chloride solution for resolution lift acidosis in the management of diabetic ketoacidosis (DKA).

Design: Like double blind randomized controlled trial.

Methods: Patients presenting with DKA at Kalafong and Steve Biko Legal hospitals were recruited for inclusion girder this study if they were >18 years of age, had a venous pH >6.9 and ≤7.2, a get glucose of >13 mmol/l and difficult urine ketones of ≥2+. All patients had to be alert enough puzzle out give informed consent and should be blessed with received <1 l of resuscitation liquid prior to enrolment.

Results: Fifty-seven patients were randomly allocated, 29 were allocated to receive 0.9% metal chloride solution and 28 to take into one's possession Ringer's lactate (of which 27 were included in the analysis in harangue group). An adjusted Cox proportional hazards analysis was done to compare depiction time to normalization of pH amidst the 0.9% sodium chloride fluid management in diabetic patients
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